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115378-21-7

methyl 2-amino-5-bromo-3-methoxybenzoate synthesis

9synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 °C
2: palladium 10% on activated carbon; hydrogen / tetrahydrofuran; methanol / 18 h / 20 °C
3: N-Bromosuccinimide / N,N-dimethyl-formamide / 0.5 h / 0 °C

References:

GREEN CROSS CORP.GREEN CROSS CORPORATION;CHOI, SOONGYU;SONG, KWANG-SEOP;LEE, SUK HO;KIM, MIN JU;SEO, HEE JEONG;PARK, EUN-JUNG;KONG, YOUNGGYU;PARK, SO OK;KANG, HYUNKU;JUNG, MYUNG EUN;LEE, KINAM;KIM, HYUN JUNG;LEE, JUN SUNG;LEE, MIN WOO;KIM, MI-SOON;HONG, DONG HO;KANG, MISUK JP5876570, 2016, B2