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methyl 2-chlorobenzo[d]oxazole-6-carboxylate synthesis

2synthesis methods
-

Yield:819076-91-0 89%

Reaction Conditions:

with thionyl chloride;N,N-dimethyl-formamide for 0.25 h;Reflux;

References:

Liu, Weiguo;Shao, Pengcheng P.;Liang, Gui-Bai;Bawiec, John;He, Jiafang;Aster, Susan D.;Wu, Margaret;Chicchi, Garry;Wang, John;Tsao, Kwei-Lan;Shang, Jin;Salituro, Gino;Zhou, Yun-Ping;Li, Cai;Akiyama, Taro E.;Metzger, Daniel E.;Murphy, Beth Ann;Howard, Andrew D.;Weber, Ann E.;Duffy, Joseph L. [ACS Medicinal Chemistry Letters,2018,vol. 9,# 11,p. 1082 - 1087] Location in patent:supporting information