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methyl 2-ethoxyacetate synthesis

7synthesis methods
-

Yield:17640-26-5 91%

Reaction Conditions:

with thionyl chloride at 0;

Steps:

Procedure for Preparation of Methyl 2-Alkoxyacetates 3a-c

General procedure: Compound 3 was prepared as a colourless liquidaccording to the literature [11]. The compound 3a, 3b and 3cwere obtained in 85, 91 and 96% yield, respectively.

References:

Su, Na-Na;Xiong, Li-Xia;Yu, Shu-Jing;Zhang, Xiao;Cui, Can;Li, Zheng-Ming;Zhao, Wei-Guang [Combinatorial Chemistry and High Throughput Screening,2013,vol. 16,# 6,p. 484 - 493]