![](/CAS/GIF/6141-58-8.gif)
METHYL 2-METHYL-3-FUROATE synthesis
- Product Name:METHYL 2-METHYL-3-FUROATE
- CAS Number:6141-58-8
- Molecular formula:C7H8O3
- Molecular Weight:140.14
![Methyl 2-diazo-3-oxobutanoate](/CAS/20200331/GIF/CB52317307.gif)
24762-04-7
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![Ethyl vinyl ether](/CAS/GIF/109-92-2.gif)
109-92-2
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$16.00/25mL
![METHYL 2-METHYL-3-FUROATE](/CAS/GIF/6141-58-8.gif)
6141-58-8
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$48.79/25g
Yield: 85%
Reaction Conditions:
with dirhodium tetraacetate in 1,2-dichloro-ethane at 20 - 80; for 8 h;Inert atmosphere;
Steps:
General procedure for the synthesis of furan 3-carboxylatederivatives
General procedure: To a solution a-diazo ester 3a (318 mg, 2 mmol) and Rh2(OAc)4 (2 mol %) in DCE (4 mL) under nitrogen atmosphere and at room temperature was added a solution of ethyl vinyl ether (216 mg, 0.288 mL, 3 mmol) in DCE (2 mL) was added through a syringe. The reaction mixture was heated at 80°C for 8 h. After the completion of the reaction as indicated by the TLC, the reaction mixture was cooled to room temperature and purified by column chromatography using a pet ether/ethyl acetate 19:1 mixture as eluent to afford the pyrrole 4a.
References:
Kuruba, Bharath Kumar;Vasanthkumar, Samuel;Emmanuvel, Lourdusamy [Tetrahedron,2017,vol. 73,# 22,p. 3093 - 3098]
![Vinyl acetate](/CAS/GIF/108-05-4.gif)
108-05-4
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![Methyl 2-diazo-3-oxobutanoate](/CAS/20200331/GIF/CB52317307.gif)
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![METHYL 2-METHYL-3-FUROATE](/CAS/GIF/6141-58-8.gif)
6141-58-8
147 suppliers
$48.79/25g
![Spiro[cyclopropane-1,2'-[7]oxabicyclo[2.2.1]hept[5]ene]-6'-carboxylic acid, 1'-methyl-3'-oxo-, methyl ester](/CAS/20210111/GIF/122889-56-9.gif)
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![METHYL 2-METHYL-3-FUROATE](/CAS/GIF/6141-58-8.gif)
6141-58-8
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$48.79/25g
![Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-](/CAS/20210305/GIF/1000210-73-0.gif)
1000210-73-0
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![Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-](/CAS/20210305/GIF/1000210-73-0.gif)
1000210-73-0
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![Methyl acetoacetate](/CAS/GIF/105-45-3.gif)
105-45-3
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$5.00/5g
![METHYL 2-METHYL-3-FUROATE](/CAS/GIF/6141-58-8.gif)
6141-58-8
147 suppliers
$48.79/25g