METHYL 4-(3-PYRIDINYL)BENZOATE synthesis

13synthesis methods

Product Name:METHYL 4-(3-PYRIDINYL)BENZOATE
CAS Number:90395-47-4
Molecular formula:C13H11NO2
Molecular Weight:213.23

626-60-8 Synthesis

626-60-8
358 suppliers
$13.00/5g

99768-12-4 Synthesis

99768-12-4
356 suppliers
$10.00/1g

90395-47-4
20 suppliers
$311.00/1g

Yield:90395-47-4 92%

Reaction Conditions:

Stage #1: 3-Chloropyridine;4-methoxycarbonylphenylboronic acidwith palladium diacetate;(R)-6-dicyclohexylphoshino-6'-diphenylphosphino-3,3'-dimethoxy-2,2',4,4'-tetramethyl-1,1'-biphenyl in dodecane;butan-1-ol at 25; for 0.0833333 h;Inert atmosphere;Glovebox;Suzuki-Miyaura Coupling;
Stage #2: with cesiumhydroxide monohydrate in dodecane;water;butan-1-ol at 80; for 4 h;Glovebox;Inert atmosphere;Suzuki-Miyaura Coupling;

References:

Yang, Junfeng;Liu, Sijia;Zheng, Jian-Feng;Zhou, Jianrong [European Journal of Organic Chemistry,2012,# 31,p. 6248 - 6259,12] Location in patent:supporting information

619-42-1 Synthesis