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ChemicalBook CAS DataBase List Methyl 4-hydroxybenzo[b]thiophene-5-carboxylate

Methyl 4-hydroxybenzo[b]thiophene-5-carboxylate synthesis

2synthesis methods
3-Furancarboxylic acid, 5-ethoxy-4,5-dihydro-2-(2-thienyl)-, methyl ester

1280722-83-9
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Yield:246177-37-7 81%

Reaction Conditions:

with indium(III) triflate in dichloromethane at 25; for 24 h;Inert atmosphere;homo-Nazarov cyclization;

References:

Phun, Lien H.;Patil, Dadasaheb V.;Cavitt, Marchello A.;France, Stefan [Organic Letters,2011,vol. 13,# 8,p. 1952 - 1955] Location in patent:supporting information; experimental part