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ChemicalBook CAS DataBase List Methyl 5-(4-methoxyphenyl)-5-oxopentanoate

Methyl 5-(4-methoxyphenyl)-5-oxopentanoate synthesis

13synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: sulfuric acid / toluene / 2 h / 80 °C / Inert atmosphere; Sealed tube
2: NADPH; 9-(2-mesityl)-10-methylacridinium perchlorate; oxygen; ketoreductase-P2-C02 / acetonitrile; water / 24 h / 23 °C / Irradiation; Enzymatic reaction

References:

Betori, Rick C.;May, Catherine M.;Scheidt, Karl A. [Angewandte Chemie - International Edition,2019,vol. 58,# 46,p. 16490 - 16494][Angew. Chem.,2019,vol. 131,p. 16642 - 16646,5]