methyl 5-(bromomethyl)nicotinate synthesis
- Product Name:methyl 5-(bromomethyl)nicotinate
- CAS Number:877624-38-9
- Molecular formula:C8H8BrNO2
- Molecular Weight:230.06
29681-45-6
180 suppliers
$8.00/1g
877624-38-9
68 suppliers
$389.00/1g
Yield:-
Reaction Conditions:
with N-Bromosuccinimide;dibenzoyl peroxide in tetrachloromethane; for 3 h;Heating / reflux;
Steps:
14
To a solution of methyl 5-methylnicotinate (5 g, 33 mmol) in carbon tetrachloride (200 mL) was added NBS (5.9 g, 1 equiv) and dibenzoyl peroxide (1.2 g, 0.15 equiv). The reaction was refluxed for 3 h, then was cooled to RT to give compound 14A. The carbon tetrachloride solution containing compound 14A was used without further purification.
References:
US2006/235028,2006,A1 Location in patent:Page/Page column 30
129747-52-0
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877624-38-9
68 suppliers
$389.00/1g