ChemicalBook CAS DataBase List METHYL 5-NITRO-1H-INDAZOLE-3-CARBOXYLATE

METHYL 5-NITRO-1H-INDAZOLE-3-CARBOXYLATE synthesis

5synthesis methods

Product Name:METHYL 5-NITRO-1H-INDAZOLE-3-CARBOXYLATE
CAS Number:78155-75-6
Molecular formula:C9H7N3O4
Molecular Weight:221.17

67-56-1 Synthesis

67-56-1
739 suppliers
$9.00/25ml

78155-76-7 Synthesis

78155-76-7
92 suppliers
$50.00/250mg

METHYL 5-NITRO-1H-INDAZOLE-3-CARBOXYLATE

78155-75-6
70 suppliers
$43.00/250mg

Yield:78155-75-6 64%

Reaction Conditions:

with sulfuric acid at 10; for 6 h;Reflux;

Steps:

Methyl 5-nitro-1H-indazole-3-carboxylate (7)

Conc. H2SO4 (19.323 mmol) was added drop wise to areaction mixture of 8 g 6 (38.64 mmol) in 80 cm3methanol over a period of half an hour below 10 C. Thereaction mixture was refluxed for 6 h. The reaction masswas cooled to room temperature and poured into crushedice, filtered, and recrystallized from ethanol to afford 7.Yellow color solid; yield 64 % (5.45 g); m.p.: 234-236 C.

References:

Sreenivasulu, Reddymasu;Sujitha, Pombala;Jadav, Surender Singh;Ahsan, Mohamed Jawed;Kumar, C. Ganesh;Raju, Rudraraju Ramesh [Monatshefte fur Chemie,2017,vol. 148,# 2,p. 305 - 314]

67-56-1 Synthesis

67-56-1
739 suppliers
$9.00/25ml

201230-82-2 Synthesis