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ChemicalBook CAS DataBase List methyl 8-oxooctanoate

methyl 8-oxooctanoate synthesis

8synthesis methods
3946-32-5 Synthesis
SUBERIC ACID MONOMETHYL ESTER

3946-32-5
186 suppliers
$12.00/1g

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Yield:-

Steps:

Multi-step reaction with 2 steps
1: 98 percent / BH3*THF / tetrahydrofuran / 12 h / Ambient temperature
2: 1.) oxalyl chloride, DMSO, 2.) Et3N / 1.) CH2Cl2, -78 deg C, 2 h, 2.) CH2Cl2, -78 deg C to room temp.

References:

Okuma, Kentaro;Hirabayashi, Syun-ichi;Ono, Masaaki;Shioji, Kosei;Matsuyama, Haruo;Bestmann, Hans J. [Tetrahedron,1998,vol. 54,# 17,p. 4243 - 4250]