Methyl piperazine-1-carboxylate hydrochloride synthesis
- Product Name:Methyl piperazine-1-carboxylate hydrochloride
- CAS Number:873697-75-7
- Molecular formula:C6H13ClN2O2
- Molecular Weight:180.6326
219509-79-2
30 suppliers
$129.00/100mg
873697-75-7
51 suppliers
$45.00/10mg
Yield:873697-75-7 99%
Reaction Conditions:
with hydrogenchloride in dichloromethane;ethyl acetate at 20; for 1 h;
Steps:
12.1 Synthesis of compound piperazine-1,3-carboxylate hydrochloride
The compound 1-tert-butoxycarbonyl-2,4-piperazine carboxylate (0.18g, 0.61mmol) in dichloromethane(6mL) was added HCl in ethyl acetate solution (4M, 3mL), stirred at rt for 1h, the solvent was removed to give awhite solid 146mg: 1,3-piperazine compound Two carboxylate hydrochloride, yield: 99%.
References:
CN105399698,2016,A Location in patent:Paragraph 0618; 0622; 0623
142-64-3
179 suppliers
$11.00/25g
79-22-1
2 suppliers
$38.00/1000g
873697-75-7
51 suppliers
$45.00/10mg
110-85-0
552 suppliers
$5.00/5G
79-22-1
2 suppliers
$38.00/1000g
873697-75-7
51 suppliers
$45.00/10mg