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ChemicalBook CAS DataBase List Methyl2-(2-amino-4-(trifluoromethyl)phenyl)acetate
13544-08-6

Methyl2-(2-amino-4-(trifluoromethyl)phenyl)acetate synthesis

5synthesis methods
-

Yield:13544-08-6 99%

Reaction Conditions:

with hydrogen;5%-palladium/activated carbon in tetrahydrofuran at 20;

Steps:



Compound 133 is hydrogenated in THF at room temperature using H2 and Pd-C (5%). The catalyst is removed by filtration and the filtrate is evaporated to dryness. Yield : 99 %, 134

References:

WO2005/75425,2005,A2 Location in patent:Page/Page column 230