ChemicalBook CAS DataBase List Methyl2-bromo-5-(trifluoromethoxy)benzoate

Methyl2-bromo-5-(trifluoromethoxy)benzoate synthesis

1synthesis methods

Product Name:Methyl2-bromo-5-(trifluoromethoxy)benzoate
CAS Number:1150114-81-0
Molecular formula:C9H6BrF3O3
Molecular Weight:299.04

83265-56-9 Synthesis

2-Amino-5-(trifluoromethoxy)benzoic acid

83265-56-9
114 suppliers
$10.00/250mg

Methyl2-bromo-5-(trifluoromethoxy)benzoate

1150114-81-0
33 suppliers
$215.00/1g

Yield:-

Steps:

Multi-step reaction with 2 steps
1: potassium carbonate / N,N-dimethyl-formamide / 20 °C
2: hydrogen bromide; sodium nitrite / water / 0.5 h / 0 °C

References:

SYNGENTA CROP PROTECTION AG;SIKERVAR, Vikas;SEN, Indira;EMERY, Daniel;MUEHLEBACH, Michel;RENDLER, Sebastian;STOLLER, André;BUCHHOLZ, Anke WO2020/174094, 2020, A1