N-(1-naphthyl)benzenesulfonamide synthesis
- Product Name:N-(1-naphthyl)benzenesulfonamide
- CAS Number:15309-82-7
- Molecular formula:C16H13NO2S
- Molecular Weight:283.34
Yield:15309-82-7 65%
Reaction Conditions:
with potassium pyrosulfite;tetrabutyl-ammonium chloride;potassium carbonate in acetonitrile at 130; for 24 h;Sealed tube;
Steps:
16 Example 16
Add 109 mg of the above nitroaromatics to the dry sealed tube,146 mg of phenylboronic acid, and 460 mg of K 2S2O5, 166 mg of potassium carbonate, 184 mg of tetrabutylammonium chloride and 3 mL of acetonitrile, then tighten the screw cap of the tube, and react at 130 ° C. for 24 h.After the reaction, it was filtered through celite, concentrated, and passed through a silica gel column to obtain 111 mg of the product in a 65% yield.
References:
CN110372463,2019,A Location in patent:Paragraph 0107-0111
