N-(1H-1,3-benzimidazol-2-yl)benzenesulfonamide synthesis
- Product Name:N-(1H-1,3-benzimidazol-2-yl)benzenesulfonamide
- CAS Number:13068-57-0
- Molecular formula:C13H11N3O2S
- Molecular Weight:273.31
![N-[bis(methylsulfanyl)methylidene]benzenesulfonamide](/CAS/20180531/GIF/13068-20-7.gif)
Yield:13068-57-0 74 %
Reaction Conditions:
with tetrabutylammomium bromide;potassium carbonate in water;Microwave irradiation;Green chemistry;Reagent/catalyst;Solvent;Wavelength;
Steps:
2.1.2. Method B
General procedure: A mixture of 0.001 mol diamine 3a-d, 0.001/0.0012 mol dimethyl(arylsulfonyl)dithioimidocarbonate (4a-c) 1/1.5/3 Eq of the appropriatebasic agent and 30-95 % mass of the solvent was placed in a roundbottom flask. For solvent-free reactions, the mixture was triturated in amortar and transferred to a round bottom flask, then whipped with astirring rod. The 0.1 Eq TBAB was also added in some variants. The flaskwas placed in the MW reactor and the reaction was carried out for 1-5min, heated for 2-8 h or placed in an ultrasonic bath and the reactionwas carried out for 20-60 min. Due to the possibility of 3a-b decomposition,care was taken that the reaction mixture did not get hotter than150 C. After this time, a sample was taken for analysis. Then, 5 ml ofwater was added to the reaction mixture and the resulting product wasfiltered off.
References:
Zar?ba, Przemys?aw;Drabczyk, Anna K.;Wnorowski, Artur;Pindelska, Edyta;Latacz, Gniewomir;Ja?kowska, Jolanta [Ultrasonics Sonochemistry,2022,vol. 90,art. no. 106165]
