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ChemicalBook CAS DataBase List N-(4-BroMophenyl)-N'-ethyl urea
82745-18-4

N-(4-BroMophenyl)-N'-ethyl urea synthesis

2synthesis methods
-

Yield: 95%

Reaction Conditions:

in dichloromethane at 20; for 1 h;

Steps:

3 Example 3: Synthesis of 1-(4-bromophenyl)-3-ethylurea (YF-3)
At room temperature, add 4-bromoisocyanate (1.2 g, 6.06 mmol) to a single-necked flask,Dichloromethane (200 mL) was stirred and dissolved, and a solution of ethylamine (0.33 g, 7.27 mmol) in 20 mL of dichloromethane was added dropwise to the reaction flask. A large amount of solid was quickly precipitated, and the stirring was continued for 1 h. Suction filtration,Obtained 1.40 g of white solid, yield 95%

References:

301 Military Hospital;Yin Fan CN110437140, 2019, A Location in patent:Paragraph 0067-0069