ChemicalBook CAS DataBase List N-(4-Methoxybenzyl)-4-nitrobenzaMide, 97%

N-(4-Methoxybenzyl)-4-nitrobenzaMide, 97% synthesis

7synthesis methods

Product Name:N-(4-Methoxybenzyl)-4-nitrobenzaMide, 97%
CAS Number:107680-88-6
Molecular formula:C15H14N2O4
Molecular Weight:286.28

1-(4-NITROPHENYL)-2-PYRIDINIUM-1-YLETHAN-1-ONE BROMIDE

25407-30-1
4 suppliers
$28.60/50mg

2393-23-9 Synthesis

2393-23-9
462 suppliers
$20.00/25g

N-(4-Methoxybenzyl)-4-nitrobenzaMide, 97%

107680-88-6
7 suppliers
inquiry

Yield:107680-88-6 76%

Reaction Conditions:

with potassium carbonate in acetonitrile at 80; for 8 h;

Steps:

II. General synthetic procedure for the preparation of compounds (3a-u, 5a-i and 7a-g)

General procedure: To a stirred solution of a pyridinium salt of phenacyl bromide (1 mmol) and thebenzylamine/benzyl alcohol/amine (1 mmol) was added in CH3CN and allowed to stir. K2CO3was added to the reaction mixture and refluxed for 8 h. The reaction progress was monitoredby using TLC. After complete consumption of the starting materials, the CH3CN wasevaporated under reduced pressure and the crude reaction mixture was diluted with EtOAc (35mL) and washed with water (10 mL) and brine (10 mL), then dried over anhydrous sodiumsulfate and concentrated to yield the crude amide, which was purified by using silica gel columnchromatography.

References:

Manasa, Kesari Lakshmi;Tangella, Yellaiah;Krishna, Namballa Hari;Alvala, Mallika [Beilstein Journal of Organic Chemistry,2019,vol. 15,p. 1864 - 1871] Location in patent:supporting information

2393-23-9 Synthesis

2393-23-9
462 suppliers
$20.00/25g

62-23-7 Synthesis