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ChemicalBook CAS DataBase List N-(5-AMINOPENTYL)-1-NAPHTHALENESULFONAMIDE HCL

N-(5-AMINOPENTYL)-1-NAPHTHALENESULFONAMIDE HCL synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 90 percent / 1M NaOH / tetrahydrofuran / 2 h
2: 60 percent / urea / 4 h / 180 - 200 °C
3: 76 percent / 1.) phenyliodosyl bis(trifluoroacetate), 2.) HCl conc. / 1.) MeCN-H2O, RT, 6 h, 2.) H2O

References:

Pavlidis, V. H.;Chan, E. D.;Pennington, L.;McParland, M.;Whitehead, M. [Synthetic Communications,1988,vol. 18,# 4,p. 1615 - 1624]