N-Acetyl carnosine synthesis
- Product Name:N-Acetyl carnosine
- CAS Number:56353-15-2
- Molecular formula:C11H16N4O4
- Molecular Weight:268.27
3025-95-4
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$5.00/1g
71-00-1
715 suppliers
$7.00/5g
56353-15-2
302 suppliers
$11.00/250mg
Yield:56353-15-2 97.9%
Reaction Conditions:
with 2-chloro-1,3-dimethylimidazolinium chloride in ethanol at 40; for 3 h;Concentration;Reagent/catalyst;Solvent;Temperature;
Steps:
17 preparation of N-acetyl-L-carnosine crude(IV)
In a 500 mL reaction flask,Add anhydrous ethanol 300mL,80 g of N-acetyl-β-alanine (0.611 mol)86.1 g L-histidine (0.555 mol),98 g of DMC (0.582 mol),Heating up to 40 ,Reaction for 3 hours,Cooling to 5 ,Filter,The filter cake was rinsed with 150 mL of anhydrous ethanol,Solid-dried product (IV) 145g,The yield was 97.9%HPLC purity> 98.8%.
References:
CN105461632,2016,A Location in patent:Paragraph 0046
3025-95-4
141 suppliers
$5.00/1g
56353-15-2
302 suppliers
$11.00/250mg
71-00-1
715 suppliers
$7.00/5g
56353-15-2
302 suppliers
$11.00/250mg