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ChemicalBook CAS DataBase List N-BENZYL ASPARTIC ACID

N-BENZYL ASPARTIC ACID synthesis

4synthesis methods
-

Yield:5555-22-6 62%

Reaction Conditions:

Stage #1: maleic anhydridewith lithium hydroxide in dimethyl sulfoxide at 50;
Stage #2: benzylamine in dimethyl sulfoxide at 125;Michael addition;

References:

Piispanen, Peter S.;Pihko, Petri M. [Tetrahedron Letters,2005,vol. 46,# 16,p. 2751 - 2755]

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