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N-Boc-1-ethynylcyclobutanamine synthesis

1synthesis methods
N-Boc-1-[(trimethylsilyl)ethynyl]cyclobutanamine

1268810-15-6
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N-Boc-1-ethynylcyclobutanamine

1268810-16-7
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Yield:1268810-16-7 91%

Reaction Conditions:

with potassium fluoride in water;N,N-dimethyl-formamide at 20; for 24 h;

References:

Kozhushkov, Sergei I.;Wagner-Gillen, Karsten;Khlebnikov, Alexander F.;Demeijere, Armin [Synthesis,2010,# 23,art. no. T17810SS,p. 3967 - 3973] Location in patent:experimental part