N-Cyclohexyl-2-benzothiazolesulfenamide synthesis
11synthesis methods
- Product Name:N-Cyclohexyl-2-benzothiazolesulfenamide
- CAS Number:95-33-0
- Molecular formula:C13H16N2S2
- Molecular Weight:264.41
The synthetic method of N-Cyclohexyl-2-benzothiazolesulfenamide (CBS) mainly has sodium hypochlorite oxidization, Oxygen Catalytic Oxidation method, electrolytic oxidation, chlorine oxidation process, hydrogen peroxide oxidation method etc. at present, oxidizing process has raw material and is easy to get, the advantages such as equipment requirements is the highest. Product yield is high, and technique is simple and widely used by institute both at home and abroad. This method is to carry out condensation with 2-benzothiazolyl mercaptan (hereinafter referred to as M) in the presence of an oxidizer with cyclohexylamine to generate CBS.
Yield:95-33-0 96%
Reaction Conditions:
with oxygen in water at 60; under 3000.3 Torr; for 4 h;Autoclave;
Steps:
1-8 Specific example 8:
2 mmol of 2-mercaptobenzothiazole, 8 mmol of cyclohexylamine, 1 wt% of cobalt catalyst, 8 mL of water were added to a high-pressure reaction kettle, and oxygen was passed in until the pressure stabilized at 0.4 MPa and heated in an oil bath At 60 ° C. for 4 h, a white solid was formed, filtered, washed, and dried, and the yield was 96%.
References:
Liaocheng University;Huang Xianqiang;Qi Yuquan;Zhao Wenli;Li Chunxia;Zheng Jun;Liu Sen;Gu Xiaoyu CN110305075, 2019, A Location in patent:Sheet 0021-0028
