N-CYCLOHEXYLPHTHALAMIC ACID synthesis

6synthesis methods

Product Name:N-CYCLOHEXYLPHTHALAMIC ACID
CAS Number:19357-06-3
Molecular formula:C14H17NO3
Molecular Weight:247.29

85-44-9 Synthesis

85-44-9
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$9.00/5g

108-91-8 Synthesis

108-91-8
591 suppliers
$10.00/5mL

19357-06-3
9 suppliers
$504.89/5g

Yield:19357-06-3 99%

Reaction Conditions:

in ethyl acetate at 20; for 18 h;

Steps:

Procedure for the synthesis of intermediates 2a-2l

General procedure: To a mixture of phthalic anhydride in ethyl acetate (1.0 g,6.8 mmol), various substituted amine derivatives (6.8 mmol)were added. The reaction was stirred at room temperature for18 h. After completion of the reaction, an equivalent volumeof n-hexane was added to the mixture, and the precipitatedmaterial was filtered off. The residue was washed up by theuse of n-hexane, diluted aqueous HCl solution, and distilledwater to afford the target intermediates 2a-2l.

References:

Mahjoub, Mahdi;Mahboubi-Rabbani, Smohammad;Vahabpour, Rouhollah;Zarghi, Afshin;Rezaee, Elham;Tabatabai, Sayyed Abbas [Medicinal Chemistry Research,2022,vol. 31,# 11,p. 1916 - 1930]

85-44-9 Synthesis

85-44-9
753 suppliers
$9.00/5g

108-91-8 Synthesis

108-91-8
591 suppliers
$10.00/5mL