N-HYDROXY-2-PYRIDIN-2-YL-ACETAMIDINE synthesis

Yield:39102-29-9 100%

Reaction Conditions:

with hydroxylamine hydrochloride;sodium in methanol;

Steps:

52.D D.

D. 1-(4-Methylpiperazin-1-yl)-7-(3-(pyrid-2-ylmethyl)-1,2,4-oxadiaz-5-ylnaphthalene Sodium (0.183 g, 7.96 mmol), hydroxylamine hydrochloride (0.570 g, 8.20 mmol), and (2-pyridyl)acetonitrile (0.375 g, 3.17 mmol) and methanol (5 mL) were used to prepare (2-pyridyl)acetamidoxime (0.55 g, >100%) as described above.

References:

US6166020,2000,A