N-methoxy-N-methylCyclopentaneacetamide synthesis
1synthesis methods
- Product Name:N-methoxy-N-methylCyclopentaneacetamide
- CAS Number:134560-38-6
- Molecular formula:C9H17NO2
- Molecular Weight:171.24
Yield:134560-38-6 83%
Reaction Conditions:
Stage #1: 2-cyclopentylacetic acidwith trichloroacetonitrile;triphenylphosphine in dichloromethane at 20; for 1 h;Inert atmosphere;
Stage #2: N,O-dimethylhydroxylamine*hydrochloridewith triethylamine in dichloromethane at 20; for 1 h;Inert atmosphere;
References:
Kim, Joong-Gon;Jang, Doo Ok [Bulletin of the Korean Chemical Society,2010,vol. 31,# 1,p. 171 - 173] Location in patent:experimental part