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ChemicalBook CAS DataBase List N-Methyl-D-phenylalanine tert-butyl ester
114525-95-0

N-Methyl-D-phenylalanine tert-butyl ester synthesis

5synthesis methods
N-Methyl-D-phenylalanine tert-butyl ester

114525-95-0
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: potassium carbonate / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere
2: potassium carbonate / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere
3: caesium carbonate; lithium hydroxide; mercaptoacetic acid / N,N-dimethyl-formamide; water / 60 °C

References:

Laura, Medve;Ronan, Gealageas;Vy, Lam Bao;Valentin, Guillaume;Omar, Castillo-Aguilera;Virgyl, Camberlein;Piveteau, Catherine;Melissa, Rosell;Charlotte, Fleau;Sandrine, Warenghem;Julie, Charton;Julie, Dumont-Ryckembusch;Damien, Bosc;Florence, Leroux;Peter, van Endert;Benoit, Deprez;Rebecca, Deprez-Poulain [European Journal of Medicinal Chemistry,2021,vol. 211,art. no. 113053]