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ChemicalBook CAS DataBase List N-METHYLAZA-12-CROWN-4
69978-45-6

N-METHYLAZA-12-CROWN-4 synthesis

2synthesis methods
84227-47-4 Synthesis
1-BENZYL-1-AZA-12-CROWN-4

84227-47-4
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: 85 percent / H2 / Pd/C / acetic acid / 15 h / 60 °C / 2280 Torr
2: 1.) K2CO3, 2.) LiAlH4 / 1.) THF, 2.) RT, 18 h

References:

Calverley, Martin J.;Dale, Johannes [Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry,1982,vol. 36,# 4,p. 241 - 248]

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