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ChemicalBook CAS DataBase List N-Methylpiperazine--d8

N-Methylpiperazine--d8 synthesis

1synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: sodium hydride / tetrahydrofuran; mineral oil / 20 °C / Cooling with ice
2: hydrogenchloride / isopropyl alcohol / 50 °C / Cooling with ice

References:

Chai Tai Tianqing Pharmaceutical Group Co., Ltd.;ZHANG, Yinsheng;LIU, Baomin;YANG, Beibei EP3381925, 2018, A1