N,N-Dibenzylacrylamide synthesis
- Product Name:N,N-Dibenzylacrylamide
- CAS Number:57625-28-2
- Molecular formula:C17H17NO
- Molecular Weight:251.32
Yield:57625-28-2 100%
Reaction Conditions:
with N-ethyl-N,N-diisopropylamine in tetrahydrofuran at -78 - 20; for 1.33333 h;
Steps:
A.6.A
A round bottom flask was charged with tetrahydrofuran (3750 mL) and cooled to-78 C under nitrogen. Acryloyl chloride, (55.7 g, 48. 9mL, 0.615 mol) and diisopropylethylamine (87.3 g, 118 mL, 0.676 mol) were added followed by the slow addition (over a period of 20 minutes) ofdibenzylamine (109.6 g, 106 mL, 0.555 mol). The reaction mixture was allowed to warm up to room
References:
WO2005/49602,2005,A1 Location in patent:Page/Page column 115; 116
