ChemicalBook CAS DataBase List N,N-Diethylcyanoacetamide

N,N-Diethylcyanoacetamide synthesis

13synthesis methods

Product Name:N,N-Diethylcyanoacetamide
CAS Number:3010-02-4
Molecular formula:C6H12N2
Molecular Weight:112.17

109-89-7
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$10.00/5g

590-17-0 Synthesis

590-17-0
326 suppliers
$5.00/5g

3010-02-4
80 suppliers
$138.00/25mL

Yield: 90%

Reaction Conditions:

in ethyl acetate

Steps:

S.21 Synthesis of diethylaminoacetonitrile (Amine 21)
Synthesis Example 21 Synthesis of diethylaminoacetonitrile (Amine 21) At 0° C., 12.0 g of bromoacetonitrile was added to 14.6 g of diethylamine. The mixture was heated to 20° C. over 10 hours. Ethyl acetate was added to the reaction mixture, and the resulting solids were filtered off. Distillation yielded diethylaminoacetonitrile (boiling point: 170° C., yield: 90%). IR (thin film): ν=2976, 2222, 1461, 1389, 1322, 1206, 1093, 984 cm^{-1 13}C-NMR (75 MHz in CDCl₃): δ=12.6, 40.5, 47.9, 114.8

References:

Shin-Etsu Chemical Co., Ltd. US6743564, 2004, B2