ChemicalBook CAS DataBase List N,N-diethyloctanamide

N,N-diethyloctanamide synthesis

10synthesis methods

Product Name:N,N-diethyloctanamide
CAS Number:996-97-4
Molecular formula:C12H25NO
Molecular Weight:199.33

124-07-2 Synthesis

124-07-2
701 suppliers
$6.00/25g

88-10-8 Synthesis

88-10-8
229 suppliers
$10.00/5g

996-97-4
57 suppliers
$52.00/50 mg

Yield: 98%

Reaction Conditions:

with triethylamine at 20; for 0.333333 h;

Steps:

4 Example 4. Preparation of N,N-diethyloctanamide
152 g ( 158 ml, 1 Mol) of octanoic acid and 136 g ( 127 ml. 1 Mole) N,N-diethyl carbamoyl chloride are taken in a 1 liter two-necked round-bottom flask fitted with air condenser which is placed over a magnetic stirrer. To this, 121 g ( 167 ml, 1.2 Mole) of triethvlaminc is added using a pressure-equalizing funnel fitted in the side neck of the round bottom flask at room temperature. After complete addition, the reaction m ixture is stirred constantly for 20 minutes at room temperature. The reaction mixture is then treated with 250 ml of water and the two layers are separated. Pure and colorless N,N-diethyloctanamide is obtained by vacuum distillation of organic layer which is the product. Purity of the compound is analyzed using GC-MS, which is more than 99.5%. The yield of the compound is 95 g (98%).

References:

DIRECTOR GENERAL, DEFENCE RESEARCH & DEVELOPMENT ORGANISATION;RAO, Ambati Narasimha;GANESAN, Kumaran;VIJAYARAGHAVAN, Rajagopalan WO2013/65059, 2013, A1 Location in patent:Page/Page column 14