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ChemicalBook CAS DataBase List N-(Propan-2-Yl)-1H-Indole-5-Carboxamide(WXC04015)

N-(Propan-2-Yl)-1H-Indole-5-Carboxamide(WXC04015) synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: lithium hydroxide monohydrate / water; tetrahydrofuran / 90 h / 20 °C
2: 6-chloro-3-((dimethylamino)(dimethyliminio)methyl)-1H-benzo[d][1,2,3]triazol-3-ium-1-olatehexafluorophosphate(V) / N,N-dimethyl-formamide / 20 °C

References:

Mistry, Shailesh N.;Shonberg, Jeremy;Draper-Joyce, Christopher J.;Klein Herenbrink, Carmen;Michino, Mayako;Shi, Lei;Christopoulos, Arthur;Capuano, Ben;Scammells, Peter J.;Lane, J. Robert [Journal of Medicinal Chemistry,2015,vol. 58,# 17,p. 6819 - 6843]