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78641-29-9

N-(propan-2-yl)quinolin-3-amine synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 83 percent / 25percent aq. NH3 / CuSO4*5H2O / 24 h / 140 - 150 °C
2: p-toluenesulfonic acid, molecular sieves 3 Angstroem / xylene / 20 h / Heating
3: NaBH4 / ethanol / 0.25 h / Heating

References:

Schoenen, Beate;Zymalkowski, Felix [Archiv der Pharmazie,1981,vol. 314,# 5,p. 464 - 470]