N-tert-Butoxycarbonyl 3-IodotyraMine synthesis

6synthesis methods

Product Name:N-tert-Butoxycarbonyl 3-IodotyraMine
CAS Number:788824-50-0
Molecular formula:C13H18INO3
Molecular Weight:363.19

64318-28-1
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$19.00/1g

788824-50-0
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$140.00/5mg

Yield:788824-50-0 91%

Reaction Conditions:

with Iodine monochloride in methanol;dichloromethane at 20; for 2 h;

Steps:

6 Synthesis of compound 36

Weighing compound 35 (11.72 g, 50 mmol) was placed in a 500 mL three-necked flask,Methanol (5 mL) and dichloromethane (95 mL) were added,Then, 50 ml of iodine chloride in dichloromethane (8.10 g, 50 mmol, 1 eq)Stirred at room temperature for 2 hours,Thin layer chromatography TLC (PE: EA = 3: 1) showed that the reaction was complete,The reaction solution was washed three times with 250 mL of water,Dispensing,Dried over anhydrous sodium sulfate,concentrate,The product (16.60 g, 91%)

References:

CN104829593,2017,B Location in patent:Paragraph 0062; 0151; 0154; 0155

24424-99-5 Synthesis