N5,N5-dimethylpyridine-2,5-diamine synthesis
- Product Name:N5,N5-dimethylpyridine-2,5-diamine
- CAS Number:39856-52-5
- Molecular formula:C7H11N3
- Molecular Weight:137.18
38772-04-2
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39856-52-5
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Yield:39856-52-5 94%
Reaction Conditions:
with hydrogen;palladium 10% on activated carbon in ethanol at 25; under 760.051 Torr;
Steps:
14
A solution OF DIMETHYL- (6-NITRO-PYRIDIN-3-YL)-AMINE (0.64 g, 3.83 mmol) in ethanol (45 ML) was treated with 10% palladium on activated carbon (203 mg). The reaction mixture was stirred under a positive pressure of hydrogen gas (balloon) at 25°C and atmospheric pressure overnight. The catalyst was then filtered off through a pad of celite, and the celite pad was washed well with ethanol. The filtrate was concentrated in vacuo to afford N5, N 5-DIMETHYL-PYRIDINE-2, 5-diamine (493.6 mg, 94%) as a dark red- purple oil: EI-HRMS m/e calcd for C7H11N3 (M+) 137.0953, found 137.0957.
References:
WO2004/52869,2004,A1 Location in patent:Page 99
39856-50-3
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39856-52-5
32 suppliers
$175.00/50mg