ChemicalBook CAS DataBase List Omethoate

Omethoate synthesis

5synthesis methods

Product Name:Omethoate
CAS Number:1113-02-6
Molecular formula:C5H12NO4PS
Molecular Weight:213.19

96-30-0 Synthesis

96-30-0
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$16.00/5g

23754-87-2 Synthesis

23754-87-2
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1113-02-6
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$55.00/100mg

Yield:1113-02-6 96.1%

Reaction Conditions:

with potassium iodide in methanol at 65; for 10 h;

Steps:

1.3; 2.3; 3.3; 4.3; 5.3; 6.3; 7.3; 8.3 (3) Recycling experiment of mother liquor prepared by O,O-dimethyl-S-(N-methylcarbamoylmethyl)phosphorothioate
The preparation mother liquid (129 mL) of O,O-dimethyl-S-(N-methylcarbamoylmethyl)phosphorothioate in Example 1 which had been reused 6 times was added with methanol to 130 ml. Add 32.82 g (0.2 mol) of the sodium O,O-dimethylthiophosphate prepared in the step (2), 21.5 g (0.2 mol) of 2-chloro-N-methylacetamide prepared in the step (1) and 1.66 g (0.01 mol) of potassium iodide were reacted at 65 ° C for 10 hours, and then the heating was stopped. After naturally dropping to room temperature, the salt formed by the reaction is filtered off, Rotating to remove the solvent, That is, 40.98 g of light yellow O,O-dimethyl-S-(N-methylcarbamoylmethyl)phosphorothioate was obtained, the yield was 96.1%; The purity by GC was 95.22%; the water content of the product was 0.044%.

References:

Henan Chemical Institute Co., Ltd.;Huo Erfu;Cheng Weiqin;Feng Ming;Wang Bonan;Wang Yanhua;Chang Shuhao;Dong Guangxia;Yang Shuai;Wang Yinan CN109651432, 2019, A Location in patent:Paragraph 0114; 0119; 0120

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