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Oxazole, 4-iodo- synthesis

1synthesis methods
Oxazole, 4-iodo-

1224742-18-0
4 suppliers
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1210372-47-6 Synthesis
2-iodo-4-phenyl-1,3-oxazole

1210372-47-6
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Oxazole, 4-iodo-2-phenyl-

1210372-46-5
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Yield:1210372-47-6 64% ,1224742-18-0 15%

Reaction Conditions:

with potassium phosphate;palladium diacetate;4,5-bis(diphenylphosphino)-9,9-dimethylxanthene in tetrahydrofuran at 60; for 8 h;Inert atmosphere;regioselective reaction;Suzuki coupling;

References:

Strotman, Neil A.;Chobanian, Harry R.;He, Jiafang;Guo, Yan;Dormer, Peter G.;Jones, Christina M.;Steves, Janelle E. [Journal of Organic Chemistry,2010,vol. 75,# 5,p. 1733 - 1739] Location in patent:supporting information; experimental part