ChemicalBook CAS DataBase List P-CRESOL-D3 (METHYL-D3)

P-CRESOL-D3 (METHYL-D3) synthesis

5synthesis methods

Product Name:P-CRESOL-D3 (METHYL-D3)
CAS Number:108561-00-8
Molecular formula:C7H5D3O
Molecular Weight:111.16

767-00-0 Synthesis

767-00-0
558 suppliers
$6.00/25g

108561-00-8
18 suppliers
$275.00/50mg

Yield:108561-00-8 90%

Reaction Conditions:

with palladium on activated charcoal;deuterium in hexane;water-d2;ethyl acetate at 100; under 15001.5 Torr; for 24 h;Solvent;Pressure;Reagent/catalyst;Temperature;

Steps:

13 Example 13In this Example, an aromatic deuterated methyl compound was prepared by the following preparation method,The reaction is as follows:

4-Cyanophenol (1 g) and palladium on carbon (0.1 g) were mixed in n-hexane: ethyl acetate:Deuterium water (10 mL: 1 mL: 1 mL), 2 MPa of deuterium gas,100 degrees stirring for 24 hours, after the reaction was filtered to give 4-deuteromethylphenol,Yield 90%, deuterium rate 98%.

References:

CN107353176,2017,A Location in patent:Paragraph 0079; 0080; 0081; 0082; 0083

14202-49-4 Synthesis