ChemicalBook CAS DataBase List (Pentafluoroethyl)benzene

(Pentafluoroethyl)benzene synthesis

10synthesis methods

Product Name:(Pentafluoroethyl)benzene
CAS Number:309-11-5
Molecular formula:C8H5F5
Molecular Weight:196.12

591-50-4 Synthesis

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309-11-5
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Yield:309-11-5 95%

Reaction Conditions:

at 50; for 24 h;

Steps:

6 EXAMPLE 6

To an aryl iodide substrate (0.2 mmol) were added a CuC2F5 solution prepared as described in Example 5(0.35 mL; 1.2 equiv) and 1,3-bis(trifluoromethyl)benzene (internal standard; 15.5 mL). This mixture was kept at 23°C or50°C or first at 23°C and then at 50°C for a certain period of time. The conversions of the CuC2F5 and yields of thecorresponding pentafluoroethylated products were determined by quantitative 19F NMR analysis. Conversion of thestarting aryl iodide was determined by GC-MS. See Table 1 for specifics.

References:

EP2835374,2015,A1 Location in patent:Paragraph 0194

108-86-1 Synthesis