Pentanoic acid, 2,2,4-trimethyl- synthesis

8synthesis methods

Product Name:Pentanoic acid, 2,2,4-trimethyl-
CAS Number:866-72-8
Molecular formula:C8H16O2
Molecular Weight:144.21

78-77-3 Synthesis

78-77-3
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$14.00/5g

547-63-7 Synthesis

547-63-7
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$13.00/5g

866-72-8
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Yield:866-72-8 30%

Reaction Conditions:

Stage #1: Methyl isobutyratewith n-butyllithium;diisopropylamine in tetrahydrofuran;hexane; for 0.5 h;Inert atmosphere;
Stage #2: Isobutyl bromide in tetrahydrofuran;hexane; for 20.1667 h;Inert atmosphere;
Stage #3: with sodium hydroxide in methanol;water at 80; for 24 h;Inert atmosphere;

References:

Kiyokawa, Kensuke;Watanabe, Tomoki;Fra, Laura;Kojima, Takumi;Minakata, Satoshi [Journal of Organic Chemistry,2017,vol. 82,# 22,p. 11711 - 11720]

78-77-3 Synthesis

78-77-3
329 suppliers
$14.00/5g