ChemicalBook CAS DataBase List Perfluoroisobutyric acid

Perfluoroisobutyric acid synthesis

6synthesis methods

Product Name:Perfluoroisobutyric acid
CAS Number:335-10-4
Molecular formula:C4HF7O2
Molecular Weight:214.04

677-69-0 Synthesis

677-69-0
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124-38-9
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$214.00/14L

335-10-4
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Yield:335-10-4 60%

Reaction Conditions:

Stage #1: perfluoroisopropyl iodide;carbon dioxidewith zinc in N,N-dimethyl-formamide at 60; for 2 h;Sonication;
Stage #2: with hydrogenchloride in water;N,N-dimethyl-formamide;Temperature;

Steps:

1

Add 50 mL of N,N-dimethylformamide and 13 g of zinc powder to a 150 mL three-necked flask, and turn on the ultrasound. The ultrasonic power is100W, carbon dioxide was introduced into the solution, and 15 mL of heptafluoro-2-iodoalkane was added dropwise when heated to 60 ° C. The feed time was 1Hours, reaction time (including feed time) is 2 hours; after the reaction is over, 100 mL of 6 mol/L hydrochloric acid is added to the reaction solution.Acidification, separation and removal of the aqueous phase gave the intermediate heptafluoroisobutyric acid (II) in a yield of about 60%.

References:

CN108276272,2018,A Location in patent:Paragraph 0029; 0030; 0033