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Phenol, 4-(4-pyrimidinyl)- (9CI) synthesis

2synthesis methods
-

Yield:23380-78-1 46 %

Reaction Conditions:

with toluene-4-sulfonic acid;1,1,1,3,3,3-hexamethyl-disilazane at 215;Sealed tube;Microwave irradiation;Schlenk technique;

References:

Bartholomew, G. Logan;Carpaneto, Filippo;Sarpong, Richmond [Journal of the American Chemical Society,2022,vol. 144,# 48,p. 22309 - 22315] Location in patent:supporting information Bartholomew, G. Logan;Carpaneto, Filippo;Sarpong, Richmond [Journal of the American Chemical Society,2023,vol. 145,# 2,p. 1472 - 1472] Location in patent:supporting information