Phosphinic acid, methyl(3-oxopropyl)- (9CI) synthesis
3synthesis methods
- Product Name:Phosphinic acid, methyl(3-oxopropyl)- (9CI)
- CAS Number:121795-01-5
- Molecular formula:C4H9O3P
- Molecular Weight:136.09
Yield:121795-01-5 92%
Reaction Conditions:
Stage #1: methylphosphinic acid chloride;acrolein in hexane at 20 - 40;
Stage #2: with water for 2 h;
Steps:
7 Example 7
cast 40 grams of allyl aldehyde and 40 grams of n-hexane into the reaction flask, start stirring, the control temperature 20 ~ 40 ° C,98% was added dropwise 68 g of compound 21,The reaction 4 ~ 8 hours, then dropwise added 13 grams of water, the reaction was stirred for 2 hours to produce 18 compounds, yield 92%.
References:
CN102372738,2017,B Location in patent:Paragraph 0102; 0103
