Pimavanserin synthesis
- Product Name:Pimavanserin
- CAS Number:107456-06-4
- Molecular formula:C14H15NO2
- Molecular Weight:229.27
Yield:107456-06-4 100 %
Reaction Conditions:
Stage #1: 4-aminomethylphenol;4-hydroxy-benzaldehydewith sodium sulfate in methanol;Inert atmosphere;Reflux;
Stage #2: with sodium tetrahydroborate in tetrahydrofuran;methanol at 20;Inert atmosphere;
References:
Di Noja, Simone;Garrido, Marina;Gualandi, Lorenzo;Ragazzon, Giulio [Chemistry - A European Journal,2023] Location in patent:supporting information
123-08-0
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