Piperidine, 4-[(3,5-difluorophenyl)methyl]- synthesis
- Product Name:Piperidine, 4-[(3,5-difluorophenyl)methyl]-
- CAS Number:794500-98-4
- Molecular formula:C12H15F2N
- Molecular Weight:211.25
159635-49-1
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Yield:-
Steps:
Multi-step reaction with 2 steps
1.1: 9-BBN / tetrahydrofuran
1.2: Pd(dppf)Cl2; K2CO3 / tetrahydrofuran; dimethylformamide / Heating
2.1: 100 percent / HCl / dioxane; CH2Cl2
References:
Ting, Pauline C.;Lee, Joe F.;Wu, Jie;Umland, Shelby P.;Aslanian, Robert;Cao, Jianhua;Dong, Youhao;Garlisi, Charles G.;Gilbert, Eric J.;Huang, Ying;Jakway, James;Kelly, Joseph;Liu, Zhidan;McCombie, Stuart;Shah, Himanshu;Tian, Fang;Wan, Yuntao;Shih, Neng-Yang [Bioorganic and Medicinal Chemistry Letters,2005,vol. 15,# 5,p. 1375 - 1378]
461-96-1
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2265-91-0
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