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112077-95-9

Propanamide, N-(4-aminophenyl)-N-methyl- synthesis

3synthesis methods
Propanamide, N-methyl-N-(4-nitrophenyl)-

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Propanamide,  N-(4-aminophenyl)-N-methyl-

112077-95-9
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-

Yield:-

Reaction Conditions:

with hydrogen;palladium 10% on activated carbon in methanol; for 4 h;

Steps:

1.3

Step 3: Synthesis of N-(4-aminophenyl)-N-methylpropionamidePalladium and carbon (10%) was added to the solution of N-methyl-N-(4-nitrophenyl) propionamide (1.17g) in methanol (3OmL). The reaction was stirred under hydrogen for 4 hours. The solution was filtered through celite and used for next step without purification. MS m/z: 179.23 (M+1).

References:

WO2010/129053,2010,A2 Location in patent:Page/Page column 113-114