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Pyrazinecarbonyl chloride, 3-chloro- (9CI) synthesis

5synthesis methods
55557-52-3 Synthesis
3-Chloropyrazine-2-carbonitrile

55557-52-3
242 suppliers
$12.00/5g

-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: sodium hydroxide; water / Reflux
2: thionyl chloride; N,N-dimethyl-formamide / toluene / 1 h / 95 °C

References:

Semelkova, Lucia;Konecna, Klara;Paterova, Pavla;Kubicek, Vladimir;Kunes, Jiri;Novakova, Lucie;Marek, Jan;Naesens, Lieve;Pesko, Matus;Kralova, Katarina;Dolezal, Martin;Zitko, Jan [Molecules,2015,vol. 20,# 5,p. 8687 - 8711]