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16082-13-6

PYRIDAZINE-3,4-DICARBOXYLIC ACID DIETHYL ESTER synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 98 percent / sulfonyl chloride / 1,2-dichloro-ethane / 1 h / 20 - 31 °C
2: 82 percent / triethylamine / 1,2-dichloro-ethane / 19 h
3: 100 percent / bromine, acetic acid / 23 h / 23 °C

References:

Vors, Jean-Pierre [Journal of Heterocyclic Chemistry,1990,vol. 27,# 3,p. 579 - 582]