Pyridine, 4-[1-(phenylmethyl)-3-pyrrolidinyl]- synthesis
- Product Name:Pyridine, 4-[1-(phenylmethyl)-3-pyrrolidinyl]-
- CAS Number:145105-06-2
- Molecular formula:C16H18N2
- Molecular Weight:238.33
100-43-6
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Yield:145105-06-2 82%
Reaction Conditions:
Stage #1: 4-vinylpyridine;N-benzyl-N-(methoxymethyl)-N-[(trimethylsilyl)methyl]amine in dichloromethane at -5; for 0.5 h;
Stage #2: trifluoroacetic acid in dichloromethane; for 6 h;
References:
Kurkin;Sumtsova;Yurovskaya [Chemistry of Heterocyclic Compounds,2007,vol. 43,# 1,p. 34 - 40]