Quinoline, 4-iodo-6,7-dimethoxy- synthesis
- Product Name:Quinoline, 4-iodo-6,7-dimethoxy-
- CAS Number:1582788-20-2
- Molecular formula:C11H10INO2
- Molecular Weight:315.11
666734-51-6
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Yield:1582788-20-2 74 %
Reaction Conditions:
Stage #1: 4-bromo-6,7-dimethoxyquinolinewith hydrogenchloride in tetrahydrofuran;1,4-dioxane;water at 20;
Stage #2: with sodium iodide in acetonitrile at 90;
References:
Abell, Joseph C.;Bold, Christian P.;Vicens, Laia;Jentsch, Tom;Velasco, Noelia;Tyler, Jasper L.;Straker, Robert N.;Noble, Adam;Aggarwal, Varinder K. [Organic Letters,2023,vol. 25,# 2,p. 400 - 404] Location in patent:supporting information